Dysport for Wrinkle Reduction by Dr. Amir Moradi of San Diego

Dr. Moradi was on the advisory board for Dysport in 2008 prior to its approval by the FDA. Since then he has been an Advisor, Lecturer, and Trainer for Dysport and is considered an expert injector of this neuromodulator.

What is DYSPORT (abobotulinumtoxinA)?

Dysport is a purified protein very similar in function to Botox®. Once injected in to the muscle it will attach itself to specialized receptors at the end of the nerves and block the transmission of signals from the nerves to the muscle. Dysport is used in the muscles of the face to reduce frown lines for a rejuvenated look.

How Does Dysport Work?

Dysport works the same as Botox. The active substance in Dysport is a botulinum neurotoxin type A complex (same as Botox), which acts at the level of the neuromuscular junction in the targeted muscle. Dysport is a neuromuscular blocking toxin which acts to block acetylcholine release at motor nerve ends and reduces muscular function. The U.S. Food and Drug Administration (FDA) approved Dysport in late April 2009. The approval included two separate indications, the temporary improvement in the appearance of moderate to severe glabella lines in adults younger than 65 years of age, and the treatment of cervical dystonia in adults to reduce the severity of abnormal head position and neck pain.

Where Can Dysport be Used?

Dysport like Botox is FDA approved for the glabella lines and like Botox, can also be used off-label in the lines around the eyes, mouth and neck. Other indications may include the treatment of excessive sweating under the arms (these treatment are Off-Label).

How long does Dysport last?

On average about 3-4 months.

How Long has Dysport been Used?

Dysport has been used in patient care in the United Kingdom since 1991; Dysport has marketing authorizations in 76 countries for therapeutic use and in 27 countries for aesthetic use. Dysport was initially developed and subsequently approved in many markets around the world, outside the U.S., for the treatment of movement disorders such as cervical dystonia (spasmodic torticollis), blepharospasm (involuntary eye closure), hemifacial spasm and various forms of muscle spasticity, including post-stroke arm spasticity, spasticity of the lower limbs (calf) in adults and children with cerebral palsy. It was later developed for the treatment of a wide variety of neuromuscular disorders and aesthetic medicine.

Are Dysport and Botox the same?

Dysport and Botox are similar proteins. Like any other medications, Dysport and Botox have specific dosages that are unique to each one.

What are risks of Dysport?

The effects of Dysport and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening, and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity, but symptoms can also occur in adults, particularly in those patients who have underlying conditions that would predispose them to these symptoms. 
The dosing Units of Dysport are not the same as and are not interchangeable with those of other botulinum toxin products.

Recommended dose and frequency of administration should not be exceeded. The clinical effects of treatment may be exacerbated in patients with neuromuscular disorders. Dysport is contraindicated in patients with infection at the proposed injection site, an allergy to cow’s-milk protein or a known hypersensitivity to any botulinum toxin product or its components. Dysport is not recommended for use in children or pregnant women. If you are interested in Dysport in San Diego, contact us to request a complimentary consultation to find out if Dysport is right for you.